Beneficial effects of sound exposure on auditory cortex development in a mouse model of Fragile X Syndrome
Background: Fragile X syndrome (FXS) is the most common genetic cause of autism and intellectual disability.Fragile X mental retardation gene (Fmr1) knock-out (KO) mice display core deficits of FXS, including abnormally increased sound-evoked responses, and show a delayed development of parvalbumin (PV) cells.Here, we present the surprising result